Pathogen 1
Bacterium
Official achievements confirm it can complete a Heart run.
Confirmed roster
All 7 Pathogens in Pathogenic
Meet the complete playable roster named in official release information and Steam achievements, including the two-player Diatom and secret lil collector.
Choose by the job you need
The roster cards separate confirmed facts from playstyle guidance. They are not a ranking: a Pathogen that is comfortable for a first run may be less suitable for a secret-route attempt or a two-player session.
Use the beginner guide for the shared run loop, then choose the roster member whose constraints match your plan. Keep hidden unlock conditions marked as hidden rather than copying an unverified community claim.
- Bacterium is the baseline choice for learning the shared editor, rooms and boss loop.
- Diatom is the two-player choice; plan separate input devices before starting.
- Amoeba and Nanobot reward deliberate shape and slot planning rather than a fixed shopping list.
- Helminth, Fungal Spore and lil collector have distinct constraints; use their dedicated guide notes before treating a player build as universal.
Pathogen 2
Helminth
The developer confirmed that defeating the Intestine boss unlocks Helminth.
Pathogen 3
Nanobot
The official launch devlog described a modular shape that starts at 1 HP with Armor-focused survival.
Pathogen 4
Fungal Spore
Official achievements confirm it can complete a Heart run.
Pathogen 5
Amoeba
The June 15 demo update introduced it as a three-slot shape that gains slots through level-up layouts.
Pathogen 6
Diatom
The February 12 demo update introduced it as a local co-op Pathogen controlled in two halves.
Pathogen 7
lil collector
Its name is confirmed by Steam; the unlock condition remains hidden.
Secret Pathogen; official sources hide its unlock requirement.
Diatom was introduced as a two-player Pathogen, with one player controlling each half. Exact starting layouts and upgrade details can change after balance updates.
Compare traits, trade-offs and unlocks →